Uji Aktivitas Antijamur Pada α-guaiene Minyak Nilam Terhadap Jamur Microsporum gypseum ATCC 14683 dan Tricophyton mentagrophytes ATCC 16404
نویسندگان
چکیده
Minyak nilam mengandung sejumlah besar senyawa golongan seskuiterpen. Senyawa α-guaiene merupakan seskuiterpen mayor yang diduga memiliki kemampuan sebagai antimikroba. Kemampuan antijamur belum banyak dibuktikan, khususnya pada spesies jamur Microsporum gypseum ATCC 14683 dan Tricophyton mentagrophytes 16404. Tujuan penelitian ini adalah untuk mengetahui adanya aktivitas antijmur minyak berbagai konsentrasi terhadap pertumbuhan M. T. dari zona hambat terbentuk. Penelitian eksperimental dengan metode difusi sumuran diameter daya (DDH). Bahan digunakan fraksi I fraksinasi 38.8% α-guaiene. Kontrol positif ketokonazol 2% flukonazol 2%, sedangkan kontrol negatif n-heksana. Perlakuan faktor 20, 40, 60, 80, 100%. Hasil diperoleh menunjukkan bahwa mampu menghambat mentagrophytes. Diameter bening mulai terbentuk 40% meningkat 60% lalu menunjukan tren menurun hingga terbesar sebesar 12.14 mm 60%, DDH 100% yaitu 3.163 mm. Ketokonazol menghasilkan penghambatan rata-rata 14.1 14 gypseum, 28.67 35 gypseum. N-heksana pelarut sekaligus tidak penghambatan.
منابع مشابه
Dermatophytosis, Microsporum canis, Trichophyton mentagrophytes, Microsporum gypseum
Overview: The fungal skin disease dermatophytosis has come to be called ringworm because of the appearance of the skin lesion that characteristically occurs with this disorder: a circular area of hair loss with a red, raised outer rim. These lesions result from an inflammatory reaction to the fungus. Most often, dogs and cats are infected by the Microsporum canis fungus, but other types of fung...
متن کاملAntifungal activity of Copaifera langsdorffii Desf oleoresin against dermatophytes.
Dermatophytoses are mycoses that affect keratinized tissues in both humans and animals. The aim of this study was to investigate the antifungal activity of the oleoresin extracted from Copaifera langsdorffii Desf. against the strains Microsporum canis ATCC 32903, Microsporum gypseum ATCC 14683, Trichophyton mentagrophytes ATCC 11481 and Trichophyton rubrum CCT 5507. The antimicrobial activity w...
متن کاملEvaluation of Antifungal Effect of Silver Nanoparticles Against Microsporum canis, Trichophyton mentagrophytes and Microsporum gypseum
Background : Dermatophytosis is the common cutaneous infections in humans and animals, which is caused by the keratinophylic fungus called dermatophytes. In recent years , drug-resistance in pathogenic fungi, including dermatophytes to the current antifungal have been increased . The aim of this study was to evaluate the antifungal efficacy of AgNPs against Microsporum canis, Trichophyton menta...
متن کاملChemical composition and antifungal activity of essential oil from Eucalyptus smithii against dermatophytes.
INTRODUCTION In this study, we evaluated the chemical composition of a commercial sample of essential oil from Eucalyptus smithii R.T. Baker and its antifungal activity against Microsporum canis ATCC 32903, Microsporum gypseum ATCC 14683, Trichophyton mentagrophytes ATCC 9533, T. mentagrophytes ATCC 11480, T. mentagrophytes ATCC 11481, and Trichophyton rubrum CCT 5507. METHODS Morphological c...
متن کاملEffect of laser photocoagulation and bevacizumab intravitreal in proliferative diabetic retinopathy: review on biomarkers of oxidative stress
Latar belakang: Penelitian ini bertujuan membandingkan pengaruh fotokoagulasi laser dan bevacizumab intravitreal (BIV) terhadap penanda biologis stres oksidatif, antara lain aktivitas aldehid dehidrogenase (ALDH) plasma, kadar malondialdehid (MDA), aktivitas superoxide dismutase (SOD) dan kadar vitreal vascular endothelial growth factor (VEGF) pada penyandang retinopati diabetik (RD) proliferatif.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Jurnal Keteknikan Pertanian Tropis dan Biosistem
سال: 2022
ISSN: ['2337-6864', '2656-243X']
DOI: https://doi.org/10.21776/ub.jkptb.2022.010.01.09